Determination of strain pattern in patients with cardiac amyloidosis secondary to Multiple myeloma: a feature tracking study

A Rare Presentation of Multiple Myeloma: A Case Report of Hepatic Amyloidosis

The clinically reported case of liver involvement with multiple myeloma (MM) is rare. Amyloidosis, defined as a tissue deposition of clonal light-chain fibrils, has been reported in 10-15% of the MM patients. We described a rare MM patient with the primal presentation of fulminant hepatic failure and biliary system involvement due to amyloidosis. Our patient had the primal symptoms of hyperbili...

Feature tracking cardiac magnetic resonance in systemic light chain amyloidosis

Background Systemic light chain amyloidosis (AL) is associated with a high cardiovascular morbidity and mortality. Cardiovascular involvement and determination of prognosis is underestimated by standard imaging parameters. Recently, cardiac deformation analysis of global circumferential and longitudinal strain has been shown to have great clinical impact on the assessment of prognosis and survi...

Evaluation of myocardial strain in patients with myocardial amyloidosis using feature-tracking technique

Background Cardiac amyloidosis results in diffuse involvement of the myocardium. For non-invasive diagnosis of myocardial amyloidosis, delayed post contrast MRI is the current gold standard. However, myocardial involvement can be patchy; not infrequently the delayed enhancement images are technically limited and many patients cannot tolerate contrast due to poor renal function. Hence an alterna...

Multiple Myeloma with HBs Antigenemia Presented with Hoarseness and Systemic Amyloidosis

Prolonged QTc Interval and Polymorphic Ventricular Tachycardia in a Patient with Multiple Myeloma- associated Cardiac Amyloidosis

Systemic amyloid light chain (AL) amyloidosis (previously known as primary amyloidosis) is a multisystem disease characterized by the extracellular deposition of fibrils composed of immunoglobulin light chains within various organs. AL amyloidosis is associated with different types of monoclonal plasma cell dyscrasias, including multiple myeloma and other monoclonal gammopathies.1 Cardiac invol...